PMID- 16683687 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Quintessence Int JT - Quintessence International IS - 1936-7163 (Electronic) IP - 5 VI - 37 PST - ppublish DP - 2006 PG - 391-394 LA - en TI - In vitro antibacterial efficacy of a new chlorhexidine slow-release device FAU - Lin, Shaul AU - Lin S FAU - Levin, Liran AU - Levin L FAU - Weiss, Ervin Izhak AU - Weiss E FAU - Peled, Micha AU - Peled M FAU - Fuss, Zvi AU - Fuss Z CN - OT - agar diffusion test OT - calcium hydroxide OT - chlorhexidine OT - slow-release device AB - Objective: The aim of this study was to evaluate and compare the antibacterial effect of chlorhexidine and calcium hydroxide slow-release devices on oral bacteria. Method and Materials: The agar diffusion test was used to evaluate the antibacterial effect of the slow-release devices Activ Point (chlorhexidine; Roeko) and Calcium Hydroxide Plus Point (Roeko) on 8 anaerobic and 2 facultative oral bacterial strains, as well as 2 bacterial cultures randomly sampled from necrotic root canals and incubated in anaerobic and aerobic broth for 48 hours. The efficiency of the medicaments against the various strains was evaluated using a nonparametric test (Friedman type) and a second nonparametric test (Wilcoxon's signed rank test). Results: Activ Point produced significantly larger inhibition zones (P < .001) than the calcium hydroxide slow-release device around all tested bacterial strains. Conclusion: The chlorhexidine slow-release device (Activ Point) exhibited significant antibacterial activity in the agar diffusion test and merits study as an intracanal medicament. AID - 839675