PMID- 16683689 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Quintessence Int JT - Quintessence International IS - 1936-7163 (Electronic) IP - 5 VI - 37 PST - ppublish DP - 2006 PG - 401-408 LA - en TI - Aggressive periodontitis in a patient with chronic cutaneous lupus erythematosus: A case report FAU - Tietmann, Christina AU - Tietmann C FAU - Bissada, Nabil F. AU - Bissada N CN - OT - acute cutaneous lupus erythematosus OT - aggressive periodontitis OT - antineutrophil cytoplasmic antibodies OT - chronic cutaneous lupus erythematosus OT - cutaneous lupus erythematosus AB - Lupus erythematosus is considered to be a high risk factor for periodontitis. As an auto-immune disease of unknown origin, cutaneous lupus erythematosus (CLE) is subdivided into 3 categories: chronic (CCLE), subacute (SCLE), and acute (ACLE). While the ACLE has a high prevalence of conjunctive periodontal lesions, aggressive periodontitis in patients with CCLE has been rarely reported. This article describes the case of a patient diagnosed with aggressive periodontitis. Three months after the diagnosis of periodontitis, the patient experienced advancing hair loss (alopecia), pale fingers and toes, as well as edema in the legs and around the eyes. Skin biopsy showed follicular hyperkeratosis with perivascular mononuclear cell infiltrate. Colliquation of the basal cells, thickening of the basal lamina, and vacuolar degeneration of basal keratinocytes were also found. A lupus band test was positive, and diagnosis of CCLE was established. Three months following the treatment of lupus with antimalarial agents, the periodontal condition became stable with no further exacerbation or progression of the existing periodontitis. An 11-month postsurgical follow-up revealed stable periodontal and general medical conditions. A patient's medical history should be re-evaluated in the event of recurrence of periodontal lesions refractory to periodontal treatment. The control of systemic conditions like lupus erythematosus is essential for a good prognosis in the treatment of periodontitis as well as for the general health of the patient. AID - 839677