PMID- 29641626 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Int J Periodontics Restorative Dent JT - International Journal of Periodontics & Restorative Dentistry IS - 1945-3388 (Electronic) IS - 0198-7569 (Print) IP - 3 VI - 38 PST - ppublish DP - 2018 PG - 373-381 LA - en TI - Clinical and CBCT Evaluation of Combined Periodontal Regenerative Therapies Using Enamel Matrix Derivative and Deproteinized Bovine Bone Mineral With or Without Collagen Membrane LID - 10.11607/prd.3288 [doi] FAU - Nemoto, Yasuko AU - Nemoto Y FAU - Kubota, Takehiko AU - Kubota T FAU - Nohno, Kaname AU - Nohno K FAU - Nezu, Arata AU - Nezu A FAU - Morozumi, Toshiya AU - Morozumi T FAU - Yoshie, Hiromasa AU - Yoshie H CN - AB - Use of collagen membrane (CM) with deproteinized bovine bone mineral (DBBM) and enamel matrix derivative (EMD) in periodontal regenerative therapy was evaluated. A total of 40 intrabony defects in periodontitis patients were treated. Clinical parameters and filled bone volume (FBV) and rate (FBR) were assessed. Probing pocket depth (PPD) was reduced significantly at 12 months with CM treatment, while clinical attachment level (CAL), FBV, and FBR showed similar improvements. In stratified analyses, CM-treated thick-biotype patients showed significant improvement in PPD and CAL. Regenerative therapy with the use of EMD and DBBM showed similar improvements in periodontal tissue regeneration with or without CM. The combination with CM appeared to influence the healing of soft tissue and was effective in decreasing pocket depth. AID - 854292