OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Int J Prosthodont JT - The International Journal of Prosthodontics IS - 1942-4426 (Electronic) IS - 0893-2174 (Print) IP - 4 VI - 34 PST - ppublish DP - 2021 PG - 492-504 LA - en TI - Antagonist Wear of Zirconia Fixed Restorations In Vitro and In Vivo: A Systematic Review FAU - Gao, Wen Mo AU - Gao W FAU - Geng, Wei AU - Geng W FAU - Yan, Yu Wei AU - Yan Y FAU - Wang, Yue AU - Wang Y CN - AB - Purpose: To evaluate the wear of zirconia on natural teeth in humans in vitro and in vivo. Materials and methods: Embase, the Cochrane Database, PubMed, and the Web of Science were searched (January 2014 to May 2019), and all references were retrieved. After preliminary screening of the literature, two researchers read the full texts of the remaining literature and determined whether the literature should be included. Data and information were extracted from the included literature, then analyzed and discussed. Results: A total of 49 in vivo experiments and 229 in vitro experiments were retrieved. After duplication removal and screening, 7 in vivo studies and 13 in vitro studies were included. The results of the in vitro studies showed that fine polished zirconia causes less antagonist wear on natural teeth than other treatments with zirconia or other restorative materials. The results of the in vivo studies showed the antagonist wear of zirconia on natural teeth was within the clinically acceptable range. Conclusion: Both in vivo and in vitro studies have shown polishing can reduce the wear of zirconia on natural teeth more than glazed or veneering porcelain. However, whether glazed zirconia causes less natural tooth wear after polishing is still a matter of debate. Due to the short observation period and heterogeneity of the experiment, the above conclusions should be carefully interpreted. AID - 1079671