PMID- 34060299 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - J Adhes Dent JT - The Journal of Adhesive Dentistry IS - 1757-9988 (Electronic) IP - 3 VI - 23 PST - ppublish DP - 2021 PG - 187-200 LA - en TI - Is There Evidence that Three-step Etch-and-Rinse 
Adhesives Have Better Retention Rates than One-step 
Self-etch Adhesives in Noncarious Cervical Lesions? 
A Systematic Review and Meta-Analysis LID - 10.3290/j.jad.b1367811 [doi] FAU - Dreweck, Fabiana Dias Simas AU - Dreweck F FAU - Zarpellon, Driellen AU - Zarpellon D FAU - Wambier, Letícia Maíra AU - Wambier L FAU - Loguercio, Alessandro D. AU - Loguercio A FAU - Reis, Alessandra AU - Reis A FAU - Gomes, Osnara Maria Mongruel AU - Gomes O CN - OT - adhesive OT - meta-analysis OT - noncarious cervical lesion OT - performance OT - randomized clinical trials AB - Purpose: A systematic review and meta-analysis was conducted to compare the retention rates of 3-step etch-and-rinse (3ER) adhesives with 1-step self-etch (1SE) adhesives in noncarious cervical lesions (NCCLs). The secondary outcomes were marginal integrity and marginal discoloration. Materials and Methods: Only randomized clinical trials (RCTs) that compared 1SE with 3ER in NCCLs were included. Controlled vocabulary and keywords were combined in the search strategy for PubMed/Medline, LILACS, BBO, Web of Science, Cochrane Library, grey literature, and IADR abstracts (1990–2018). The Cochrane Risk of Bias tool (RoB) was applied to eligible studies. Meta-analyses were conducted for retention rate and secondary outcomes at different follow-up times, using the random effects model. Heterogeneity was assessed with the Cochran Q test and I2 statistics. The GRADE approach was used to assess the quality of the evidence. Results: After the removal of duplicates, title and abstract screening, 18 studies remained. Of these, 15 studies were used for meta-analysis. Fourteen out of these 15 were judged at “unclear” risk and 1 at “low” risk of bias. No significant differences between groups were observed in the different follow-up periods for retention rates 12 to 24 months (p = 0.66), 24 to 36 months (p = 0.21) and 60 months (p = 0.96). A significant difference in marginal integrity was found at 12 to 24 months (p = 0.04) and in marginal discoloration at 12 to 24 months (p = 0.003). Conclusion: There is no evidence that 3-step ER adhesives have better retention rates than 1-step SE adhesives in NCCLs. AID - 1367811