PMID- 34235909 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Quintessence Int JT - Quintessence International IS - 1936-7163 (Electronic) IP - 10 VI - 52 PST - ppublish DP - 2021 PG - 848-861 LA - en TI - Two-year outcomes following the adjunctive use of InGaAsP and Er,Cr:YSGG lasers in nonsurgical periodontal therapy in patients with stages III and IV periodontitis LID - 10.3290/j.qi.b1702285 [doi] FAU - Ciurescu, Codruta Elena AU - Ciurescu C FAU - Gutknecht, Norbert AU - Gutknecht N FAU - Ciurescu, Vlad Alexandru AU - Ciurescu V FAU - Gheorghiu, Anca AU - Gheorghiu A FAU - Franzen, Rene AU - Franzen R FAU - Arweiler, Nicole B. AU - Arweiler N FAU - Sculean, Anton AU - Sculean A FAU - Cosgarea, Raluca AU - Cosgarea R CN - OT - YSGG OT - InGaAsP OT - periodontal laser therapy OT - periodontal treatment OT - periodontitis AB - Objective: To evaluate the clinical outcomes 2 years after the adjunctive use of an InGaAsP diode and Er,Cr:YSGG laser for nonsurgical treatment of severe periodontitis. Method and materials: Forty-two patients (45.31 ± 9.78 years old, n = 22 females, n = 23 smokers) with stage III or IV grade B periodontitis were randomly treated either with laser (InGaAsP + Er,Cr:YSGG) adjunctive to subgingival debridement (test group, n = 21) or with subgingival debridement alone (control group, n = 21). Subjects in the test group received a second laser treatment in residual sites 2 months after the initial laser therapy. At baseline, and at 12 and 24 months after therapy, periodontal clinical parameters were evaluated. The primary outcome variable was the number of residual deep sites at 12 months (probing depth [PD] ≥ 6 mm). Results: One and two years after nonsurgical periodontal treatment, both groups yielded statistically significant clinical improvements. The adjunctive use of InGaAsP and Er,Cr:YSGG laser to mechanical debridement resulted in statistically significantly higher clinical (PD, clinical attachment level, bleeding on probing, number of sites with PD ≥ 5 mm, PD ≥ 6 mm, PD ≥ 7 mm) improvements (P < .05) compared to subgingival debridement alone both at 12 and 24 months after therapy. Conclusion: In patients with stage III or IV grade B periodontitis, InGaAsP and Er,Cr:YSGG used adjunctively to subgingival debridement may additionally improve the clinical outcomes compared to mechanical debridement alone over a period of 24 months. AID - 1702285