OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Int J Periodontics Restorative Dent JT - International Journal of Periodontics & Restorative Dentistry IS - 1945-3388 (Electronic) IS - 0198-7569 (Print) IP - 3 VI - 42 PST - ppublish DP - 2022 PG - 361-368 LA - en TI - The Effect of an Alloplastic Bone Substitute and Enamel Matrix Derivative on the Preservation of Single Anterior Extraction Sockets: A Histologic Study in Humans LID - 10.11607/prd.4917 [doi] FAU - Bontá, Hernán AU - Bontá H FAU - Galli, Federico Guillermo AU - Galli F FAU - Gualtieri, Ariel AU - Gualtieri A FAU - Renou, Sandra AU - Renou S FAU - Caride, Facundo AU - Caride F CN - AB - This study was designed to assess the effect of enamel matrix derivative (Emdogain, Straumann) and alloplastic bone substitute (BoneCeramic, Straumann) on new bone formation in postextraction alveolar sockets. Twenty-one patients requiring anterior single-tooth extractions and subsequent implant placement were recruited and randomly assigned to one of three treatment groups. Postextraction sockets were filled with either an alloplastic bone substitute (BoneCeramic [BC]), BC combined with Emdogain (EMD+BC), or left to heal spontaneously (SO). Histologic and histomorphometric analyses of the results were performed at 6 months postextraction. A significant increase in the percentage of new bone tissue area was found in EMD+BC compared to SO and BC groups. These findings demonstrate that compared with BC or SO, EMD+BC allowed for better formation of new bone in postextraction sockets after 6 months of healing. AID - 2974225