PMID- 31508604 OWN - Quintessenz Verlags-GmbH CI - Copyright Quintessenz Verlags-GmbH OCI - Copyright Quintessenz Verlags-GmbH TA - Chin J Dent Res JT - Chinese Journal of Dental Research IS - 1867-5646 (Electronic) IS - 1462-6446 (Print) IP - 3 VI - 22 PST - ppublish DP - 2019 PG - 165-173 LA - en TI - Changes of Microbial Community in Treated Peri-implantitis Sites: An Experimental Study in Beagle Dogs LID - 10.3290/j.cjdr.a43110 [doi] FAU - Wu, Yu Wei AU - Wu Y FAU - Zheng, Hui AU - Zheng H FAU - Li, Xue Fen AU - Li X FAU - Lu, Hui AU - Lu H FAU - Lu, Song He AU - Lu S FAU - Liu, Xu Hong AU - Liu X FAU - Zeng, Qiang AU - Zeng Q FAU - Chen, Feng AU - Chen F FAU - Lin, Jiu Xiang AU - Lin J FAU - Tang, Zhi Hui AU - Tang Z CN - OT - peri-implantitis OT - microbial communities OT - peri-implant mucositis OT - peri-implant soft tissue OT - biofilm AB - Objective: To investigate the changes of the bacterial community in the oral environment of beagle dogs to gain insights on the possible causes of failed therapy in peri-implantitis. Methods: Beagles were used as models for experimental peri-implantitis. Samples from peri-implant soft tissue (supramargin and submargin), ligature and contaminated surface of peri-implantitis sites were collected and analysed by sequencing the bacterial 16S rRNA gene. Results: The residual microbial community from the curettes-treated implant surface contained a variety of microorganisms, including periodontal pathogens, which showed no changes in their composition and structure. Conclusion: It is possible that the residual bacterial community remained unchanged and this was the cause of recurrent episodes of inflammation. AID - 851879