Purpose: To review the influence of prosthodontic and dental implant treatment on patient satisfaction and oral health-related quality of life (OHQOL) based on a systematic search of the literature. Materials and Methods: A systematic literature search was carried out for articles published between 1960 and February 2003. Details of the search process and results were reported in Part 1 of the study (Int J Prosthodont 2004;17:83-93). The included studies were categorized and evaluated according to their level of evidence, following the guidelines of the Agency for Health Care Policy and Research. The characteristics and content of the studies were analyzed and tabulated. Results: Among the 114 included studies, there were 76 publications reaching evidence level III. The results showed that the effects of compromised oral health are not limited to traditional clinical aspects, but can considerably affect patients in various activities of daily life. Twenty-four of the 38 investigations with evidence levels I and II dealt with implant stabilization of complete mandibular prostheses, comparing implant prostheses to conventional complete dentures. Fully edentulous patients experience negative impacts on OHQOL from their condition. They benefit significantly from the use of dental implants to support mandibular prostheses. However, support by more than 2 implants does not appear to further significantly increase patient satisfaction and OHQOL. Conclusions: To date, research in the field of patient-based outcomes has concentrated on dental implant treatment for the edentulous patient. Other prosthetic treatments such as single crowns, fixed and removable partial dentures, or further treatment concepts (eg, the shortened dental arch concept) are not well represented. The use of patient-centered outcome measures can help to find an individual, patient-oriented prosthetic solution.