Materials and Methods: Post-market, prospective, randomized, controlled, multi-center study
with a primary endpoint of one year. 53 subjects were randomized to receive either immediate
implant placement (test group) or delayed implant placement (control group). The mean crestal
bone-level changes from implant loading to 12 months post-implant loading were measured
using standardized, digital periapical radiographs. Changes in facial plate thickness measured on
cone-beam computed tomography (CBCT) images, implant success and survival, implant
stability, soft tissue changes, patient-centered outcomes, and adverse effects were measured to
assess outcomes between the test and control treatments at 12 months post-loading.
Results: 46 subjects completed the study (23 in each group). Mean bone changes from loading to
the 12 month follow-up were recorded with no statistically significant difference (p=0.950)
between both groups. The hypothesis was confirmed that immediate implant placement (Test) in
extraction sockets is similar to delayed placement (Control). The test group was found to be
similar to the control group (P=0.022) in terms of mean changes in facial plate thickness. Implant
survival and success were 95.8% in the test group and 92% in the control group. Stability in the
control group was superior at the time of surgery, but there was no difference between both
groups at implant loading, producing a non-significant p-value of (0.563). Conclusion: This
randomized, controlled, multi-center one-year study showed comparable outcomes 1-year after
prosthetic loading in the immediate and delayed placement groups.
Keywords: Key words: prospective study, dental Implant, marginal bone level, soft tissue, complication, randomized clinical trial.